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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Clinical significance of hyaluronan levels and its pro-osteogenic effect on mesenchymal stromal cells in myelodysplastic syndromes

Fig. 4

Effect of HA on osteogenic differentiation of MSC. a Osteogenic induction assay of MSC on surface with and without HA-coating was evaluated at day 7, day 14 and day 21 respectively. Representative micrographs of Alizarin Red S staining of HA-uncoated MSC and HA-coated MSC are shown. Magnification: 10×. b Differences with regard to osteogenic differentiation were quantified by the OD value. c Comparion of mRNA expression of osteogenic differentiation related genes (RUNX-2, BSP, ALP, COL-1, OPN, OCN) between HA-uncoated group and HA-coated group

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