Table 2 Univariate and multivariate Cox regression models for overall survival (OS) in patients who received chemotherapy beyond the first-line setting (N = 46)
N (%) | Univariate Cox regression model | Multivariate Cox regression model | |||
|---|---|---|---|---|---|
HR (95% CI) | p-value | HR (95% CI) | p-value | ||
YAP+/TP53mut(mv) | Positive vs negative 15 (32.6%) vs 31 (67.4%) | 0.39 (0.19–0.83) | 0.015 | 0.36 (0.16–0.81) | 0.013 |
ECOG-PS | 1–2 vs 0 19 (41.3%) vs 27 (58.7%) | 1.17 (0.61–2.23) | 0.636 | 1.61 (0.77–3.39) | 0.209 |
Stage | Metastatic vs locally advanced 24 (52.2%) vs 22 (47.8%) | 1.21 (0.63–2.31) | 0.564 | 1.44 (0.60–3.47) | 0.414 |
No. metastatic sites | 2–3 vs 1 16 (34.8%) vs 30 (65.2%) | 1.16 (0.60–2.24) | 0.666 | 0.68 (0.30–1.54) | 0.355 |
Taxanes | Yes vs no 25 (54.3%) vs 21 (45.7%) | 0.77 (0.40–1.48) | 0.440 | 0.72 (0.30–1.68) | 0.445 |