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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: RIP3 dependent NLRP3 inflammasome activation is implicated in acute lung injury in mice

Fig. 2

GSK872 decreased cell count IL-1β and IL-18 level in BAL fluid of LPS-induced ALI mice, as well as attenuated the histopathological injury. a HE staining of lung sections shows GSK872 treatment attenuated pulmonary injury and inflammatory cell infiltration in ALI mice. b HE staining of cytospun cells from BAL fluids. c Total cell counts of BAL fluids in Sham (PBS control), LPS and GSK872 (LPS + GSK872 treatment) groups. d Total protein level in BAL fluids. e, f IL-1β and IL-18 level in BAL fluid measured by ELISA. Each bar represents mean ± SEM (n = 6). **p < 0.01 versus sham mice; #p < 0.05 versus LPS-induced lung injury mice

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