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Table 1 Clinical characteristics of the patient groups

From: Urinary exosome miR-146a is a potential marker of albuminuria in essential hypertension

Variables

Albuminuric

No albuminuric

(n = 24)

(n = 28)

Age (years)

52.6 ± 8.4

54.6 ± 5.6

Gender (male)

66.7%

64.3%

Systolic blood pressure (mmHg)

136 ± 11

136 ± 24

Diastolic blood pressure (mmHg)

84 ± 15

88 ± 15

Pulse pressure (mmHg)

52 ± 12

48 ± 16

Glucose (mg/dL)

119 ± 45

118 ± 40

Glycated haemoglobin (%)

6.6 ± 0.3

6.0 ± 0.8

Total cholesterol (mg/dL)

202 ± 34**

174 ± 28

LDL (mg/dL)

131 ± 30**

108 ± 25

HDL (mg/dL)

51 ± 14

49 ± 11

Triglycerides (mg/dL)

148 ± 76

129 ± 59

Plasma creatinine (mg/dL)

0.86 ± 0.06

0.89 ± 0.21

Glomerular filtration rate (mL/min/1.73 m2)

97 ± 27

88 ± 19

Waist (cm)

107 ± 15

99 ± 12

Central obesity (%)

54

50

Body mass index (kg/m2)

32 ± 7

30 ± 6

Obesity (%)

50

39.3

Obesity grade (%)

 Grade I

29

18

 Grade II

8

11

 Grade III

13

11

Diabetes (%)

38

32

Dyslipidemia (%)

88

82

Smoking (%)

46

46

Ex-smoking (%)

29

14

Urinary albumin excretion/creatinine (mg/g)

162.8 ± 168.2***

3.3 ± 2.3

Antihypertensive treatment (%)

 ACEi

100

100

 ARB

93

92

 CCB

64

38

 Diuretics

64

63

  1. ACEi angiotensin converting enzyme inhibitors, ARB angiotensin II receptor antagonists, CCB calcium channel blocker, HDL high-density lipoprotein, LDL high-density lipoprotein
  2. The data are expressed as the mean ± SD, unless noted otherwise. The glomerular filtration rates were calculated using the MDRD formula. Comparisons between microalbuminuric groups: **p < 0.01, ***p < 0.001