From: Urinary exosome miR-146a is a potential marker of albuminuria in essential hypertension
Variables | Albuminuric | No albuminuric |
---|---|---|
(n = 24) | (n = 28) | |
Age (years) | 52.6 ± 8.4 | 54.6 ± 5.6 |
Gender (male) | 66.7% | 64.3% |
Systolic blood pressure (mmHg) | 136 ± 11 | 136 ± 24 |
Diastolic blood pressure (mmHg) | 84 ± 15 | 88 ± 15 |
Pulse pressure (mmHg) | 52 ± 12 | 48 ± 16 |
Glucose (mg/dL) | 119 ± 45 | 118 ± 40 |
Glycated haemoglobin (%) | 6.6 ± 0.3 | 6.0 ± 0.8 |
Total cholesterol (mg/dL) | 202 ± 34** | 174 ± 28 |
LDL (mg/dL) | 131 ± 30** | 108 ± 25 |
HDL (mg/dL) | 51 ± 14 | 49 ± 11 |
Triglycerides (mg/dL) | 148 ± 76 | 129 ± 59 |
Plasma creatinine (mg/dL) | 0.86 ± 0.06 | 0.89 ± 0.21 |
Glomerular filtration rate (mL/min/1.73 m2) | 97 ± 27 | 88 ± 19 |
Waist (cm) | 107 ± 15 | 99 ± 12 |
Central obesity (%) | 54 | 50 |
Body mass index (kg/m2) | 32 ± 7 | 30 ± 6 |
Obesity (%) | 50 | 39.3 |
Obesity grade (%) | ||
 Grade I | 29 | 18 |
 Grade II | 8 | 11 |
 Grade III | 13 | 11 |
Diabetes (%) | 38 | 32 |
Dyslipidemia (%) | 88 | 82 |
Smoking (%) | 46 | 46 |
Ex-smoking (%) | 29 | 14 |
Urinary albumin excretion/creatinine (mg/g) | 162.8 ± 168.2*** | 3.3 ± 2.3 |
Antihypertensive treatment (%) | ||
 ACEi | 100 | 100 |
 ARB | 93 | 92 |
 CCB | 64 | 38 |
 Diuretics | 64 | 63 |