Fig. 6

a Relative expression of hsa-let-7a-5p and hsa-miR-21-5p in risk groups. The relative expression of hsa-let-7a-5p, and hsa-miR-21-5p in risk groups were evaluated by measuring the difference in threshold cycle number. The expression of hsa-let-7a-5p was significantly different between HR, and HR_F (p = 0.037) while, hsa-miR-21-5p expression was significantly different between HR, and IR following radiation (p = 0.036). This may mean the function and role of hsa-miR-21-5p in PCa differs in response to radiation, based on risk category. IR intermediate risk without radiotherapy, HR high risk group without radiotherapy, IR_F intermediate risk post radiotherapy, HR_F high risk post radiotherapy. One asterisk indicates significant (p-value < 0.05) difference in miRNAs expression level between compared groups. b Fold change results for miRNAs. The fold change values of five miRNAs are shown. The y-axis represents log transformed 2^−ΔΔCt value calculated in radiation treated patients relative to pre-radiotherapy (baseline)