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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Improving knowledge on the activation of bone marrow fibroblasts in MGUS and MM disease through the automatic extraction of genes via a nonnegative matrix factorization approach on gene expression profiles

Fig. 5

Basis matrix of MM condition. Heatmap plot of the basis matrix extracted from the gene expression profile data matrix of the 10 patients with MM conditions. Eight metagenes were automatically extracted with a rank of the factorization equal to 8. Values in each column of the basis matrix have been normalized by row and sorted to show higher values on the bottom and lower values on the top of the heatmap. Due to the presented of the highest number of relevant values, metagene six was (automatically) identified as the most representative metagene of the dataset with MM condition

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