Fig. 4

Basis matrix of MGUS condition. Heatmap plot of basis matrix extracted from the gene expression profile data matrix of the 8 patients with MGUS conditions. Five metagenes were automatically extracted with a rank of the factorization = 5. Values in each column of the basis matrix have been normalized by row and sorted to show higher values on the bottom and lower values on the top of the heatmap. As highlighted by the color shades, both metagenes two and five present a significant number of important genes. Metagene two has been considered as the most representative of the whole dataset of MGUS condition since this column includes the largest number of extracted genes