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Table 3 Change in liver enzymes in plasma with 1% CHOL diet and endothelial injury (N = 4)

From: MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits

Blood plasma biomarkers Baseline After 1% CHOL + injury P-value
Free cholesterol (mg/dl) 48.5 ± 8.8 651.8 ± 167.5 0.018
Triglycerides (mg/dl) 44.3 ± 5.7 89.7 ± 15.9 0.021
GGT (U/l) 6.3 ± 0.5 10.3 ± 1.3 0.014
AST/ALT ratio 0.63 ± 0.12 1.11 ± 0.18 0.033
Total protein (g/dl) 4.9 ± 0.2 5.5 ± 0.4 NS
  1. Readings from blood plasma were compared in 1% CHOL + injury rabbits to baseline readings. Baseline readings are defined as blood plasma samples obtained prior to initiation of 1% CHOL diet. Readings in the blood were obtained at 3 months before pharmacologic triggering. The P-value displayed was obtained from the Student’s t-test comparing the baseline and before trigger readings