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Table 3 Change in liver enzymes in plasma with 1% CHOL diet and endothelial injury (N = 4)

From: MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits

Blood plasma biomarkers

Baseline

After 1% CHOL + injury

P-value

Free cholesterol (mg/dl)

48.5 ± 8.8

651.8 ± 167.5

0.018

Triglycerides (mg/dl)

44.3 ± 5.7

89.7 ± 15.9

0.021

GGT (U/l)

6.3 ± 0.5

10.3 ± 1.3

0.014

AST/ALT ratio

0.63 ± 0.12

1.11 ± 0.18

0.033

Total protein (g/dl)

4.9 ± 0.2

5.5 ± 0.4

NS

  1. Readings from blood plasma were compared in 1% CHOL + injury rabbits to baseline readings. Baseline readings are defined as blood plasma samples obtained prior to initiation of 1% CHOL diet. Readings in the blood were obtained at 3 months before pharmacologic triggering. The P-value displayed was obtained from the Student’s t-test comparing the baseline and before trigger readings
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Journal of Translational Medicine

ISSN: 1479-5876

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