Skip to main content
Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Regulatory network of circRNA–miRNA–mRNA contributes to the histological classification and disease progression in gastric cancer

Fig. 7

Proposed scheme for the roles of circHIPK3-miR-124/miR-29b axes on tumor growth and clinical progression in GC. Significantly differential expressed miRNAs were found in two pathological types of GC. Both of miR-124 and miR-29b were consistently down-regulated in GC. CircHIPK3 acted a negative regulatory role on miR-124/miR-29b expression and inhibited GC cell proliferation. The bioinformatics analyses showed that targets expression of circHIPK3-miR-124/miR-29b axes in Pathways in cancer was able to predict the status of GC and associated with individual survival time

Back to article page