Fig. 2

The expression levels of miR-124 and miR-29b in GC samples, and the regulatory role of circHIPK3-miR-124/miR-29b in GC cell. Higher Δ Ct value indicates lower expression. a, b The expression levels of miR-124 and miR-29b are significantly lower than those in corresponding normal tissues (n = 63, ***P < 0.001). c, d The association between miR124/miR-29b expression and Ming’s classification in clinical samples. e, g Expression levels of circHIPK3 was confirmed compared to control in qRT-PCR analysis after transfection. f, h Expressions of miR-124 and miR-29b were regulated by circHIPK3 compared with negative control. **P < 0.01, ***P < 0.001