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Table 4 UGT1A1 polymorphisms and clinical factors of Cox regression analysis for OS and EFS

From: Influence of UGT1A1 polymorphisms on the outcome of acute myeloid leukemia patients treated with cytarabine-base regimens

Variables in the model Overall survival Event free survival
HR (95% CI) P value HR (95% CI) P value
UGT1A1 *28/− or *6/ 0.787 (0.627–0.990) 0.040 0.959 (0.700–1.313) 0.923
Risk stratification groups:   7.8 × 10−16   9.5 × 10−5
 Low vs intermediate 0.775 (0.566–1.066) 0.117 0.686 (0.493–0.953) 0.021
 High vs intermediate 2.615 (2.024–3.377) 1.9 × 10−13 1.652 (1.188–2.297) 0.003
WBC count, × 109/l 1.003 (1.001–1.005) 0.002 1.002 (1.000–1.004) 0.095
Age (years) 1.013 (1.005–1.021) 0.002 1.004 (0.995–1.013) 0.366
  1. WBC white blood cell