Table 4 UGT1A1 polymorphisms and clinical factors of Cox regression analysis for OS and EFS
Variables in the model | Overall survival | Event free survival | ||
|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
UGT1A1 *28/− or *6/− | 0.787 (0.627–0.990) | 0.040 | 0.959 (0.700–1.313) | 0.923 |
Risk stratification groups: |  | 7.8 × 10−16 |  | 9.5 × 10−5 |
 Low vs intermediate | 0.775 (0.566–1.066) | 0.117 | 0.686 (0.493–0.953) | 0.021 |
 High vs intermediate | 2.615 (2.024–3.377) | 1.9 × 10−13 | 1.652 (1.188–2.297) | 0.003 |
WBC count, × 109/l | 1.003 (1.001–1.005) | 0.002 | 1.002 (1.000–1.004) | 0.095 |
Age (years) | 1.013 (1.005–1.021) | 0.002 | 1.004 (0.995–1.013) | 0.366 |