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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Tanshinone IIA promotes the differentiation of bone marrow mesenchymal stem cells into neuronal-like cells in a spinal cord injury model

Fig. 5

PKH67(+) cells were mainly found at the site of injury and exhibited varying colocalization with glial and neuronal cell markers. A14 Astrocytic differentiation of the transplanted BMSCs. B1D4 Neuronal differentiation of the transplanted BMSCs. Rectangles indicated the colocalization of PKH67 with GFAP, Nestin, NeuN, or NF200 (n = 3, three sections and six fields per section). E Image analysis showed that the number of transplanted BMSCs expressing Nestin, or NF200 was higher in the TIIA + BMSCs group than that in the BMSCs group (P < 0.05), while GFAP expression was higher in the BMSCs group (P < 0.05). There was no significant difference of in the number of NeuN(+) cells between the two groups (P > 0.05). Images are taken from the BMSCs only group. Data are means ± SDs. Scale bar, 50 μm

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