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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Tanshinone IIA promotes the differentiation of bone marrow mesenchymal stem cells into neuronal-like cells in a spinal cord injury model

Fig. 1

Gross findings, H&E images of injured spinal cord lesions and image analysis. A Gross findings at 1 day post-SCI and a healthy control. The yellowish connective tissue (inside rectangle) was the site of SCI. It (rectangle) showed damage and deflection compared to the healthy spinal cord. B H&E images of normal spinal cord. CF H&E images of injured spinal cord (28 days post-SCI). Damage to the spinal cord was associated with the presence of a cavity and parenchymal necrosis at 28 days after SCI. G Image analysis of cavity formation at the epicenter of the SCI. There was no significant difference between the sham and BMSCs + TIIA groups. The cystic area of the SCI group was the largest and there were differences between these groups (SCI vs TIIA, SCI vs BMSCs, SCI vs BMSCs + TIIA, TIIA vs BMSCs, TIIA vs BMSCs + TIIA, BMSCs vs BMSCs + TIIA,***P < 0.001). Scale bar: 200 μm (C-1, D-1, E-1 and F-1); 100 μm (C-2, D-2, E-2 and F-2)

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