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Table 2 Aberrant protein expression in dMMR patients

From: Comparison of immunological characteristics between paired mismatch repair-proficient and -deficient colorectal cancer patients

Aberrant protein expression Number of cases (n, %)
MMR (1) 60 (36.8)
 MLH1 11 (6.7)
 MSH2 5 (3.1)
 MSH6 35 (21.5)
 PMS2 9 (5.5)
MMR (2) 85 (52.1)
 MLH1 + MSH2 1 (0.6)
 MLH1 + MSH6 2 (1.2)
 MLH1 + PMS2 49 (30.1)
 MSH2 + MSH6 30 (18.4)
 MSH2 + PMS2 2 (1.2)
 MSH6 + PMS2 1 (0.6)
MMR (3) 13 (8.0)
 MLH1 + MSH2 + PMS2 4 (2.5)
 MLH1 + MSH6 + PMS2 6 (3.7)
 MLH1 + MSH2 + MSH6 2 (1.2)
 MSH2 + MSH6 + PMS2 1 (0.6)
MMR (4) 5 (3.1)
  1. MMR (1): negative expression of only one MMR protein
  2. MMR (2): concurrent negative expression of two MMR proteins
  3. MMR (3): concurrent negative expression of three MMR proteins
  4. MMR (4): concurrent negative expression of four MMR proteins