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Table 3 The clinicopathologic characteristics of nKlf4 and cKlf4 mutation in NPC patients

From: Nuclear Klf4 accumulation is associated with cetuximab drug-resistance and predicts poor prognosis of nasopharyngeal carcinoma

Variables

Cases

PI3K (n, %)

H-Ras (n, %)

Negative

Positive

P

Negative

Positive

P

Gender

 Male

94

79 (84.0)

15 (16.0)

0.120

78 (83.0)

16 (17.0)

0.242

 Female

74

55 (74.3)

19 (25.7)

 

56 (75.7)

18 (24.3)

 

Age (years)

 < 54

87

70 (80.5)

17 (19.5)

0.816

71 (81.6)

16 (18.4)

0.537

 ≥ 54

81

64 (79.0)

17 (21.0)

 

63 (77.8)

18 (22.2)

 

T classification

 T3

24

21 (87.5)

3 (12.5)

0.308

18 (75.0)

6 (25.0)

0.531

 T4

144

113 (78.5)

31 (21.5)

 

116 (80.6)

28 (19.4)

 

N classification

 N0

87

75 (86.2)

12 (13.8)

0.031

73 (83.9)

14 (16.1)

0.166

 N1–3

81

59 (72.8)

22 (27.2)

 

61 (75.3)

20 (24.7)

 

M classification

 M0

122

98 (80.3)

24 (19.7)

0.766

97 (79.5)

25 (20.5)

0.894

 M1

46

36 (78.3)

10 (21.7)

 

37 (80.4)

9 (19.6)

 

Clinical stage

 III

49

41 (83.7)

8 (16.3)

0.418

38 (77.6)

11 (22.4)

0.647

 IV

119

93 (78.2)

26 (21.8)

 

96 (80.7)

23 (19.3)

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