Association of the peripheral blood levels of circulating microRNAs with both recurrent miscarriage and the outcomes of embryo transfer in an in vitro fertilization process

Table 6 Alterations in peripheral blood levels of miRs

	miR levels of RM patients (vs NP women)						miR levels of non-pregnant women in IVF-ET (vs pregnant women)
	Villi		Plasma		Serum		Plasma		Serum
	FC	P	FC	P	FC	P	FC	P	FC	P
miR-23a-3p	1.602	0.322	− 1.097	0.726	− 2.252	0.002	− 1.704	0.021	1.086	0.326
miR-27a-3p	1.929	0.045	1.485	0.010	− 1.090	0.470	− 1.691	0.003	1.305	0.027
miR-29a-3p	2.676	0.031	3.926	0.001	− 1.412	0.321	− 1.316	0.069	− 1.100	0.202
miR-100-5p	9.732	0.000	2.553	0.001	− 1.014	0.948	− 1.462	0.033	− 1.261	0.007
miR-127-3p	− 1.740	0.105	2.227	0.011	− 1.807	0.011	− 1.620	0.027	1.001	0.989
miR-486-5p	− 1.663	0.220	− 1.763	0.021	2.455	0.029	− 1.113	0.593	− 1.284	0.023

In RM and NP group: Positive fold change (FC) means up-regulated in RM patients and negative fold change means down regulated in RM patients compared to NP women. In IVF-ET group: Positive fold change (FC) means up-regulated in non-pregnant women in IVF-ET and negative fold change means down regulated in non-pregnant women in IVF-ET compared to pregnant women. Results were considered significant when P < 0.05

ISSN: 1479-5876