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Table 5 Receiver operating characteristic analysis in prediction for outcome of IVF-ET by the selected miRs in peripheral blood plasma

From: Association of the peripheral blood levels of circulating microRNAs with both recurrent miscarriage and the outcomes of embryo transfer in an in vitro fertilization process

Roc index

Prediction for clinical pregnancy outcome

Model 1a (combination of the six miRs)

Model 2b (combination of miR-127a-3p and miR-486-5p)

AuROC (95% CI)*

0.62 (0.53, 0.71)

0.62 (0.53, 0.71)

Sensitivity (%)

68.1

50.0

Specificity (%)

54.1

75.3

Positive predictive value (%)

59.0

65.5

Negative predictive value (%)

63.5

60.4

Correctly classified (%)

61.0

62.3

Cut-off value

0.469a

0.533b

  1. * No significant difference in ROC area between Model 1 and Model 2
  2. aModel 1: Cut-off value = 0.469; (miR-23a-3p, 22.112194); (miR-27a-3p, 28.546087); (miR-29a-3p, 23.40597); (miR-100-5p, 28.019193); (miR-127-3p, 27.498337); (miR-486-5p, 12.804071)
  3. bModel 2: Cut-off value = 0.533; (miR-127-3p, 28.653163); (miR-486-5p, 14.214297)