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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: A novel gene-expression-signature-based model for prediction of response to Tripterysium glycosides tablet for rheumatoid arthritis patients

Fig. 3

Gene signal transduction network associated with patients’ response to TG tablets. a Gene signal transduction network based on the interaction data of 212 differentially expressed genes obtained from STRING database. Red and blue circle nodes respectively refer to the upregulated and downregulated mRNAs in the responder group compared to the non-responder group. The node sizes represented the degree values according to the ascending order. b The 16 major genes’ sub-module constructed using the direct interactions among them. Red and blue circle nodes respectively refer to the upregulated and downregulated mRNAs in the responder group compared to the non-responder group. The node sizes represented the fold-change of gene expression levels in responder and non-responder groups according to the ascending order

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