TY - JOUR AU - De Matteis, Serena AU - Molinari, Chiara AU - Abbati, Giulia AU - Rossi, Tania AU - Napolitano, Roberta AU - Ghetti, Martina AU - Di Rorà, Andrea Ghelli Luserna AU - Musuraca, Gerardo AU - Lucchesi, Alessandro AU - Rigolin, Gian Matteo AU - Cuneo, Antonio AU - Calistri, Daniele AU - Fattori, Pier Paolo AU - Bonafè, Massimiliano AU - Martinelli, Giovanni PY - 2018 DA - 2018/06/20 TI - Immunosuppressive Treg cells acquire the phenotype of effector-T cells in chronic lymphocytic leukemia patients JO - Journal of Translational Medicine SP - 172 VL - 16 IS - 1 AB - In chronic lymphocytic leukemia (CLL) disease onset and progression are influenced by the behavior of specific CD4+ T cell subsets, such as T regulatory cells (Tregs). Here, we focused on the phenotypic and functional characterization of Tregs in CLL patients to improve our understanding of the putative mechanism by which these cells combine immunosuppressive and effector-like properties. SN - 1479-5876 UR - https://doi.org/10.1186/s12967-018-1545-0 DO - 10.1186/s12967-018-1545-0 ID - De Matteis2018 ER -