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Table 1 Clinical characteristics of 173 AML patients according to VIM expression Z-score ≥ 1

From: Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia

Characteristic

Z-score (< 1) (n = 145)

Z-score (≥ 1) (n = 28)

p value

Age, median (years)

57

63.5

0.048

 Young (< 60 years)

81 (55.9%)

10 (64.3%)

0.063

 Old (> 60 years)

64 (44.1%)

18 (35.7%)

 

Sex

 Female (n, %)

68 (46.9%)

13 (46.4%)

> 0.999

 Male (n, %)

77 (53.1%)

15 (53.6%)

 

FAB

 M0 (n, %)

15 (10.3%)

1 (3.57%)

0.476

 M1 (n, %)

39 (26.9%)

5 (17.9%)

0.353

 M2 (n, %)

34 (23.5%)

4 (14.3%)

0.329

 M3 (n, %)

11 (7.59%)

5 (17.9%)

0.146

 M4 (n, %)

27 (18.6%)

7 (25.00%)

0.446

 M5 (n, %)

12 (8.28%)

6 (21.4%)

0.083

 M6 (n, %)

2 (1.38%)

0 (0.00%)

> 0.999

 M7 (n, %)

3 (2.07%)

0 (0.00%)

> 0.999

WB count, median

12.6

69.2

< 0.001

 ln (WB count), mean

2.446

3.749

< 0.001

% BM blast, median

71

82.5

0.017

% PB blast, median

34

44.5

0.253

Risk status

 Poor (n, %)

42 (29.0%)

3 (10.7%)

0.057

 Intermediate (n, %)

73 (50.3%)

19 (67.9%)

0.091

 Good (n, %)

28 (19.3%)

5 (17.9%)

> 0.999

Cytogenetic status

 Normal (n, %)

60 (41.4%)

20 (71.4%)

0.003

 Abnormal (n, %)

83 (57.2%)

7 (25.0%)

 

Transplant status

 No (n, %)

78 (53.8%)

22 (78.6%)

0.021

 Yes (n, %)

67 (46.2%)

6 (21.4%)