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Table 3 Univariate and multivariate survival analysis of clinicopathologic variables and miR-197 expression in diffuse large B cell lymphoma patients

From: Clinicopathologic implication of microRNA-197 in diffuse large B cell lymphoma

Clinicopathologic variables R-CHOP cohort, n = 43 ABC R-CHOP cohort, n = 31
UA MA UA MA
p p HR [95% CI] p p HR [95% CI]
miR-197
 Low vs. high 0.036 0.031 27.9 [1.4–569.0] 0.025 0.037 21.5 [1.2–382.6]
IPI
 High (3–5) vs. low (0–2) < 0.001 0.009 10.0 [1.8–56.1] 0.001 0.055 5.1 [1.0–26.6]
B symptoms
 Presence vs. absence 0.024 0.844 1.2 [0.3–4.8] 0.059   
Bone marrow involvement
 Presence vs. absence 0.006 0.038 15.4 [1.2–203.3] 0.029 0.046 13.5 [1.1–173.1]
Stagea
 I–II vs. III–IV 0.004    0.012   
Performance statusa
 ≥ 2 vs. 0–1 < 0.001    < 0.001   
LDHa
 Elevated vs. normal 0.005    0.005   
Number of extranodal sitesa
 ≥ 2 vs. 0–1 < 0.001    0.002   
  1. UA univariate analysis, MA multivariate analysis, 95% CI 95% confidence interval, IPI international prognostic index, LDH lactate dehydrogenase
  2. aThese variables were not included in multivariate analysis due to their close relationship with IPI