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Table 2 Comparison of miR-197 expression levels according to clinicopathologic characteristics in diffuse large B cell lymphoma patients

From: Clinicopathologic implication of microRNA-197 in diffuse large B cell lymphoma

Variables

Full cohort (n = 51)

R-CHOP cohort (n = 43)

Mean ± SD

p value

Mean ± SD

p value

Age, years

 

0.415

 

0.357

 < 60

18.2 ± 32.6

 

7.8 ± 12.0

 

 ≥ 60

12.0 ± 13.7

 

11.6 ± 13.4

 

Sex

 

0.603

 

0.353

 Male

16.0 ± 27.7

 

8.5 ± 10.4

 

 Female

12.5 ± 15.4

 

12.2 ± 15.4

 

Primary site

 

0.504

 

0.595

 Nodal

11.5 ± 15.3

 

8.6 ± 14.3

 

 Extranodal

16.2 ± 26.8

 

10.8 ± 12.3

 

Ann Arbor stage

 

0.379

 

0.731

 I, II

17.3 ± 29.2

 

10.7 ± 12.8

 

 III, IV

11.5 ± 14.1

 

9.4 ± 13.2

 

IPI groupa

 

0.664

 

0.985

 Low (0–2)

11.2 ± 13.0

 

10.1 ± 12.3

 

 High (3–5)

13.0 ± 15.6

 

10.1 ± 14.1

 

B symptomsa

 

0.737

  

 Absent

15.7 ± 27.4

 

10.4 ± 12.2

 

 Present

13.4 ± 15.6

 

9.5 ± 14.4

 

ECOG PSa

 

0.886

 

0.310

 0, 1

12.0 ± 13.8

 

10.9 ± 13.5

 

 ≥ 2

12.8 ± 16.0

 

5.1 ± 5.9

 

LDHa

 

0.466

 

0.785

 Normal

10.2 ± 13.2

 

9.5 ± 12.6

 

 Elevated

13.2 ± 14.6

 

10.6 ± 13.3

 

BM involvementa

 

0.561

 

0.452

 Absent

11.0 ± 12.5

 

9.1 ± 11.2

 

 Present

19.2 ± 24.8

 

24.1 ± 27.9

 

Number of extranodal sitesa

 

0.182

 

0.582

 0, 1

12.9 ± 15.0

 

10.7 ± 14.0

 

 ≥ 2

8.1 ± 8.0

 

8.1 ± 8.0

 

EBER

 

0.820

 

0.804

 Negative

14.1 ± 24.4

 

9.9 ± 11.2

 

 Positive

16.0 ± 19.8

 

11.2 ± 20.4

 

Hans classification

 

0.253

 

0.833

 GCB

20.7 ± 38.0

 

9.4 ± 11.5

 

 Non-GCB

12.2 ± 14.6

 

10.4 ± 13.5

 
  1. IPI international prognostic index, ECOG PS Eastern Cooperative Oncology Group Performance Status, LDH lactate dehydrogenase, BM bone marrow, EBER EBV-encoded RNA, GCB germinal center B-like
  2. aThese variables exclude missing values
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Journal of Translational Medicine

ISSN: 1479-5876

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