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Table 2 Comparison of miR-197 expression levels according to clinicopathologic characteristics in diffuse large B cell lymphoma patients

From: Clinicopathologic implication of microRNA-197 in diffuse large B cell lymphoma

Variables Full cohort (n = 51) R-CHOP cohort (n = 43)
Mean ± SD p value Mean ± SD p value
Age, years   0.415   0.357
 < 60 18.2 ± 32.6   7.8 ± 12.0  
 ≥ 60 12.0 ± 13.7   11.6 ± 13.4  
Sex   0.603   0.353
 Male 16.0 ± 27.7   8.5 ± 10.4  
 Female 12.5 ± 15.4   12.2 ± 15.4  
Primary site   0.504   0.595
 Nodal 11.5 ± 15.3   8.6 ± 14.3  
 Extranodal 16.2 ± 26.8   10.8 ± 12.3  
Ann Arbor stage   0.379   0.731
 I, II 17.3 ± 29.2   10.7 ± 12.8  
 III, IV 11.5 ± 14.1   9.4 ± 13.2  
IPI groupa   0.664   0.985
 Low (0–2) 11.2 ± 13.0   10.1 ± 12.3  
 High (3–5) 13.0 ± 15.6   10.1 ± 14.1  
B symptomsa   0.737   
 Absent 15.7 ± 27.4   10.4 ± 12.2  
 Present 13.4 ± 15.6   9.5 ± 14.4  
ECOG PSa   0.886   0.310
 0, 1 12.0 ± 13.8   10.9 ± 13.5  
 ≥ 2 12.8 ± 16.0   5.1 ± 5.9  
LDHa   0.466   0.785
 Normal 10.2 ± 13.2   9.5 ± 12.6  
 Elevated 13.2 ± 14.6   10.6 ± 13.3  
BM involvementa   0.561   0.452
 Absent 11.0 ± 12.5   9.1 ± 11.2  
 Present 19.2 ± 24.8   24.1 ± 27.9  
Number of extranodal sitesa   0.182   0.582
 0, 1 12.9 ± 15.0   10.7 ± 14.0  
 ≥ 2 8.1 ± 8.0   8.1 ± 8.0  
EBER   0.820   0.804
 Negative 14.1 ± 24.4   9.9 ± 11.2  
 Positive 16.0 ± 19.8   11.2 ± 20.4  
Hans classification   0.253   0.833
 GCB 20.7 ± 38.0   9.4 ± 11.5  
 Non-GCB 12.2 ± 14.6   10.4 ± 13.5  
  1. IPI international prognostic index, ECOG PS Eastern Cooperative Oncology Group Performance Status, LDH lactate dehydrogenase, BM bone marrow, EBER EBV-encoded RNA, GCB germinal center B-like
  2. aThese variables exclude missing values