Skip to main content
Fig. 3 | Journal of Translational Medicine

Fig. 3

From: A strategy for designing voriconazole dosage regimens to prevent invasive pulmonary aspergillosis based on a cellular pharmacokinetics/pharmacodynamics model

Fig. 3

Relationship between the total voriconazole Ce/MIC and the intracellular antifungal effect as measured by the proportion of initial incubation. a The solid black line is the fit of an mathematical model to data from the infected A549 model, and the calculated equation by WinNonlin software is: effect index = 159.4 − 143.4 × (Ce/MIC)1.1/(12.21.1 + (Ce/MIC)1.1), R2 = 0.9738. b The relationship between Ce/MIC breakpoint and intracellular antifungal effect

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us