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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: A strategy for designing voriconazole dosage regimens to prevent invasive pulmonary aspergillosis based on a cellular pharmacokinetics/pharmacodynamics model

Fig. 2

Goodness of fit fitted by sigmoidal function: extracellular concentration-dependent activity of voriconazole against intracellular A. fumigatus. The ordinate shows the change in the value of cfu (∆lg cfu) per mL of cell lysate after 24 h incubation compare with the initial intracellular conidia. a Data were plotted against the extracellular concentration (mg/L) of voriconazole. b Data were plotted against the ratio of extracellular concentration divide MIC value

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