Fig. 2From: A strategy for designing voriconazole dosage regimens to prevent invasive pulmonary aspergillosis based on a cellular pharmacokinetics/pharmacodynamics modelGoodness of fit fitted by sigmoidal function: extracellular concentration-dependent activity of voriconazole against intracellular A. fumigatus. The ordinate shows the change in the value of cfu (∆lg cfu) per mL of cell lysate after 24 h incubation compare with the initial intracellular conidia. a Data were plotted against the extracellular concentration (mg/L) of voriconazole. b Data were plotted against the ratio of extracellular concentration divide MIC valueBack to article page