Fig. 1
From: Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway
The expression of GEP in CRC. a GEP mRNA expression was significantly higher in CRC cell lines (6/8) than normal colon. b GEP mRNA expression was significantly higher in colon cancer tissues than the normal colon in the Ki colon dataset of ONCOMINE. c Representative IHC images showing no expression in normal colon (H-score = 0), high expression in tumor cells (H-score > 150), and low expression in tumor cells (H-score ≤ 150) of GEP in human CRC samples. d GEP protein expression was higher in primary CRCs (51.6%), compared to normal colonic mucosa (4.3%). (*P < 0.05; **P < 0.01)