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Table 1 Clinical, biological and histo-pathological data from the 29 patients with crescentic glomerulonephritis and DDR1 immunostaining evaluation of the crescents as positive or negative

From: Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime

Patient nb Clinical data Histological data
Diagnostic Age/gender SCreat (µmol/l) eGFR ml/min/1.73 m2 BUN mg/dl Proteinuria (g/l) Hematuria Glomeruli Cellular crescents Fibrous crescents TIF %
Total Globally sclerosed DDR1+ DDR1− DDR1+ DDR1−  
1 Goodpasture 81/F 478 8 18.9 15 pos 8 0 5 0 0 0 25
2   85/F 776 4 32.7 3.68 pos 37 23 3 0 0 2 75
3   22/M 113 > 60 5.3 1.54 pos 9 0 3 0 0 0 0
4   21/M 196 38 10 0.64 pos 14 0 7 0 0 2 10
5   72/M 117 98 10 9 pos 42 0 3 0 0 1 0
6 ANCA 82/F 678 15 26.2 2.5 pos 54 20 0 27 0 3 0
7   74/M 312 16 25.3 0.58 pos 32 0 27 1 0 2 35
8   78/F 84 58 4.3 1.39 pos 9 2 0 1 0 0 0
9   66/F 165 29 ND 0.4 neg 27 0 11 4 0 2 55
10   66/M 311 19 ND 0.6 pos 17 0 7 0 0 0 20
11   70/M 202 28 12 2.09 pos 12 1 1 0 0 3 0
12   68/M 158 40 ND 1.8 pos 24 0 10 0 0 3 30
13 IgA 45/F 88 67 ND 7 neg 28 1 19 1 0 4 40
14   84/F 310 12 11 4.93 pos 7 0 2 0 0 1 10
15   56/M 94 > 60 3.3 0.3 pos 15 0 8 0 0 0 20
16   39/F 135 43 11 1.78 pos 21 8 5 0 0 0 50
17   43/F 56 > 60 4.8 0.6 pos 17 3 3 0 0 0 30
18   74/M 180 34 15 0.7 pos 14 1 0 0 0 1 50
19   19/F 62 > 60 4.5 3 pos 44 0 12 0 0 0 15
20   19/F 57 > 60 3 1.0 pos 34 0 2 0 0 0 10
21   23/M 91 > 60 5.9 0.5 pos 52 0 7 0 0 0 0
22   64/M 99 > 60 5.1 0.4 pos 8 0 4 0 0 0 45
23   72/F 250 17 ND 2 pos 12 0 4 0 0 1 30
24   64/F 108 47 12 1.88 pos 9 0 0 1 0 1 0
25 Lupus 37/F 159 36 8.5 8.0 pos 27 0 16 3 0 3 0
26   40/F 107 56 10.2 4.05 pos 19 0 6 0 0 4 30
27   44/M 180 38 ND 4.6 pos 14 0 3 0 0 4 40
28   51/M 97 > 60 7.6 5.0 pos 47 1 9 0 0 2 10
29   52/M 102 > 60 6.88 5.0 pos 45 2 20 0 0 6 20