Table 1 Clinical, biological and histo-pathological data from the 29 patients with crescentic glomerulonephritis and DDR1 immunostaining evaluation of the crescents as positive or negative
Patient nb | Clinical data | Histological data | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diagnostic | Age/gender | SCreat (µmol/l) | eGFR ml/min/1.73 m2 | BUN mg/dl | Proteinuria (g/l) | Hematuria | Glomeruli | Cellular crescents | Fibrous crescents | TIF % | ||||
Total | Globally sclerosed | DDR1+ | DDR1− | DDR1+ | DDR1− |  | ||||||||
1 | Goodpasture | 81/F | 478 | 8 | 18.9 | 15 | pos | 8 | 0 | 5 | 0 | 0 | 0 | 25 |
2 | Â | 85/F | 776 | 4 | 32.7 | 3.68 | pos | 37 | 23 | 3 | 0 | 0 | 2 | 75 |
3 |  | 22/M | 113 | > 60 | 5.3 | 1.54 | pos | 9 | 0 | 3 | 0 | 0 | 0 | 0 |
4 | Â | 21/M | 196 | 38 | 10 | 0.64 | pos | 14 | 0 | 7 | 0 | 0 | 2 | 10 |
5 | Â | 72/M | 117 | 98 | 10 | 9 | pos | 42 | 0 | 3 | 0 | 0 | 1 | 0 |
6 | ANCA | 82/F | 678 | 15 | 26.2 | 2.5 | pos | 54 | 20 | 0 | 27 | 0 | 3 | 0 |
7 | Â | 74/M | 312 | 16 | 25.3 | 0.58 | pos | 32 | 0 | 27 | 1 | 0 | 2 | 35 |
8 | Â | 78/F | 84 | 58 | 4.3 | 1.39 | pos | 9 | 2 | 0 | 1 | 0 | 0 | 0 |
9 | Â | 66/F | 165 | 29 | ND | 0.4 | neg | 27 | 0 | 11 | 4 | 0 | 2 | 55 |
10 | Â | 66/M | 311 | 19 | ND | 0.6 | pos | 17 | 0 | 7 | 0 | 0 | 0 | 20 |
11 | Â | 70/M | 202 | 28 | 12 | 2.09 | pos | 12 | 1 | 1 | 0 | 0 | 3 | 0 |
12 | Â | 68/M | 158 | 40 | ND | 1.8 | pos | 24 | 0 | 10 | 0 | 0 | 3 | 30 |
13 | IgA | 45/F | 88 | 67 | ND | 7 | neg | 28 | 1 | 19 | 1 | 0 | 4 | 40 |
14 | Â | 84/F | 310 | 12 | 11 | 4.93 | pos | 7 | 0 | 2 | 0 | 0 | 1 | 10 |
15 |  | 56/M | 94 | > 60 | 3.3 | 0.3 | pos | 15 | 0 | 8 | 0 | 0 | 0 | 20 |
16 | Â | 39/F | 135 | 43 | 11 | 1.78 | pos | 21 | 8 | 5 | 0 | 0 | 0 | 50 |
17 |  | 43/F | 56 | > 60 | 4.8 | 0.6 | pos | 17 | 3 | 3 | 0 | 0 | 0 | 30 |
18 | Â | 74/M | 180 | 34 | 15 | 0.7 | pos | 14 | 1 | 0 | 0 | 0 | 1 | 50 |
19 |  | 19/F | 62 | > 60 | 4.5 | 3 | pos | 44 | 0 | 12 | 0 | 0 | 0 | 15 |
20 |  | 19/F | 57 | > 60 | 3 | 1.0 | pos | 34 | 0 | 2 | 0 | 0 | 0 | 10 |
21 |  | 23/M | 91 | > 60 | 5.9 | 0.5 | pos | 52 | 0 | 7 | 0 | 0 | 0 | 0 |
22 |  | 64/M | 99 | > 60 | 5.1 | 0.4 | pos | 8 | 0 | 4 | 0 | 0 | 0 | 45 |
23 | Â | 72/F | 250 | 17 | ND | 2 | pos | 12 | 0 | 4 | 0 | 0 | 1 | 30 |
24 | Â | 64/F | 108 | 47 | 12 | 1.88 | pos | 9 | 0 | 0 | 1 | 0 | 1 | 0 |
25 | Lupus | 37/F | 159 | 36 | 8.5 | 8.0 | pos | 27 | 0 | 16 | 3 | 0 | 3 | 0 |
26 | Â | 40/F | 107 | 56 | 10.2 | 4.05 | pos | 19 | 0 | 6 | 0 | 0 | 4 | 30 |
27 | Â | 44/M | 180 | 38 | ND | 4.6 | pos | 14 | 0 | 3 | 0 | 0 | 4 | 40 |
28 |  | 51/M | 97 | > 60 | 7.6 | 5.0 | pos | 47 | 1 | 9 | 0 | 0 | 2 | 10 |
29 |  | 52/M | 102 | > 60 | 6.88 | 5.0 | pos | 45 | 2 | 20 | 0 | 0 | 6 | 20 |