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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Regulatory γδ T cells induced by G-CSF participate in acute graft-versus-host disease regulation in G-CSF-mobilized allogeneic peripheral blood stem cell transplantation

Fig. 2

Proliferation of γδTreg subsets following anti-TCRγδ combined with G-CSF and/or TGF-β induction. a Kinetics of γδTreg proliferation following G-CSF or TGF-β induction during a 12-day culture period. b Proportions of γδTregs, Vδ1Tregs and Vδ2Tregs in freshly isolated PBMCs. ce The expression of CD27 and CD25 phenotype on γδTregs (c), Vδ1Tregs (d) and Vδ2Tregs (e) in γδ T cells in the three induction and control groups on day 9 of culture. The data are representative of results from independent experiments of 5 healthy donors. f Proportions of γδTregs, Vδ1Tregs and Vδ2Tregs in γδ T cells in the three inductions and control groups on day 9 of culture. g Proportions of CD25+γδTregs, CD25+Vδ1Tregs, CD25+Vδ2Tregs, CD27+γδTregs, CD27+Vδ1Tregs and CD27+Vδ2Tregs in γδ T cells in the three inductions and control groups on day 9 of culture. *P < 0.05

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