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Table 2 Flow cytometric landscape of the MO 3 months after CPB compared to pre-CPB levels

From: Acquired immunological imbalance after surgery with cardiopulmonary bypass due to epigenetic over-activation of PU.1/M-CSF

Marker Typical cellular expression to (Me [IQ25; IQ75]) t3m (Me [IQ25; IQ75]) p
MFI-MRP8 MAC M1 2372.33 [1250.74, 2977.14] 774.4 [695.33, 1032.22] 0.019
MFI CD86 Activated MO 783.88 [457.60, 990.84] 230.17 [178.29, 372.42] 0.050
MFI-CD206 MAC M2 725.00 [409.81, 1038.23] 1902.2 [905.26, 4212.51] 0.026
MFI-CD163 MAC M1 1653.80 [1400.21, 1885.59] 1335.6 [718.19, 1439.18] 0.004
TGF/LAP MAC M2 1099.53 [892.44, 1253.50] 3223 [2407.00, 3560.50] 0.003
  1. Flow cytometry reveals a persistence of MRP(high), CD206(high), CD163(high), TGF/LAP(high) and decreased expression of CD86 3 months after CPB as compared to pre-CPB values