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Table 1 Baseline characteristics of the patients

From: Acquired immunological imbalance after surgery with cardiopulmonary bypass due to epigenetic over-activation of PU.1/M-CSF

Characteristics

Age—year

68.8 ± 13.4

Sex—Male no.

11.0 (55%)

BMI (kg/m2)

29.2 ± 5.3

Preoperative WBC (109/L)

7.1 ± 1.9

Anesthesia and surgery data

 Duration of anesthesia (min)

406.4 ± 116.2

 Duration of surgery (min)

290.0 ± 109.9

 Duration of CBP (min)

138.4 ± 74.4

 Duration of X-clamp (min)

111.8 ± 55.2

 Coronary artery bypass surgery no.

8 (40%)

 Mitral valvuloplasty no.

6 (30%)

 Aortic valve replacement no.

4 (20%)

 Aortic aneurysm repair no.

2 (10%)

Transfusions

 During surgery

  Packed red blood cells (ml)

0 [0;450]

  Fresh frozen plasma (ml)

0 [0;500]

  Platelets (ml)

0 [0;300]

 In 24 h post-surgery

  Packed red blood cells (ml)

0 [0;300]

  Fresh frozen plasma (ml)

0 [0;0]

  Platelets (ml)

0 [0;0]

Total crystalloid during surgery (ml)

2000 [500;4750]

ICU stay

 APACHE score at 1 h

20.2 ± 5.0

 APACHE score at 24 h

12.7 ± 5.4

 APACHE score at 48 h

12.2 ± 4.6

Comorbidities

 Chronic heart failure

6 (30%)

 Connective tissue disease (non-active)

1 (5%)

 Peripheral vascular disease

4 (20%)

 Cerebrovascular disease

5 (25%)

 Type 2 diabetes

4 (20%)

 Liver disease

0 (0%)

 AIDS

0 (0%)

 COPD

1 (5%)

 Any tumor (last 5 year)

1 (5%)

 Renal disease moderate to severe

4 (20%)