Table 1 Demographic details for heart failure patients and healthy controls
From: Evidence for a hyper-reductive redox in a sub-set of heart failure patients
Characteristics of patients | Heart failure patients (n = 54) | Healthy controls | ||
|---|---|---|---|---|
Hyperreductive (n = 9) | Hyperoxidative (n = 23) | Normal redox (n = 22) | ||
Age in years: mean age (range)†| 50 (32–75) | 58 (34–73) | 52 (34–75) | 36.35 (18–64) |
Sex: n (% male)†| 9 (100) | 23 (100) | 21 (95) | 27 (64) |
Mean height in cm (range)†| 164 (151.7–177) | 163 (152–173) | 163 (143–178) | 165.8 (148–192) |
Mean weight in kg (range)†| 60 (50–70) | 62 (41–75) | 63 (38–100) | 62.7 (38–89) |
Body mass index (kg/m2) (range)†| 22 (19.5–24.5) | 23 (16.4–30.3) | 24 (15.2–35.4) | 22.9 (16.1–34.6) |
Hemodynamics†| ||||
 Heart rate (no. of times/min) | 97 (60–100) | 94 (74–121) | 96 (70–116) | 78 (64–98) |
 Mean systolic blood pressure (mmHg) | 129 (80–170) | 129 (80–180) | 125 (90–170) | 119 (90–190) |
 Mean diastolic blood pressure (mmHg) | 79 (60–140) | 85 (60–110) | 77 (50–110) | 76 (50–110) |
Comorbidities, %†| ||||
 DM and DM associated disorders | 5 (55) | 15 (65) | 10 (45) | – |
 Systemic hypertension | 3 (33) | 5 (22) | 6 (27) | – |
 Hypothyroidism | 0 | 4 (17) | 1 (4.5) | – |
 Chronic kidney disease | 1 (11) | 3 (13) | 0 | – |
 Anaemia | 0 | 2 (7) | 2 (9) | – |
 BPH (benign prostatic hyperplasia) | 1 (11) | 0 | 1 (4.5) | – |
 Hepatitis | 0 | 0 | 1 (4.5) | – |
 CVA (cerebrovascular accident) | 0 | 1 (4) | 0 | – |
 COPD | 1 (11) | 2 (9) | 3 (14) | – |
Cardiac disease pathology, %†| ||||
 Dilated cardiomyopathy | 5 (55) | 8 (35) | 9 (41) | – |
 Coronary artery disease | 2 (22) | 10 (43) | 10 (45) | – |
 Rheumatic heart disease | 1 (11) | 0 | 2 (9) | – |
 Ischemic heart disease | 0 | 1 (4) | 1 (4.5) | – |
 Aortoiliac disease | 1 (11) | 5 (22) | 0 | – |
 Diastolic dysfunction | 10 (43) | 7 (32) | 8 (89) | – |
 Systolic dysfunction | 16 (69.5) | 19 (86) | 9 (100) | – |
 Biventricular dysfunction | 6 (26) | 4 (18) | 0 | – |
 Pulmonary artery hypertension (PAH) | 12 (52) | 10 (45) | 4 (44) | – |
Medication, %* | ||||
 Diuretics | 5 (55) | 20 (87) | 18 (82) | – |
 β blockers | 4 (44) | 12 (52) | 12 (54) | – |
 Statins | 1 (11) | 9 (39) | 6 (27) | – |
 ACE inhibitors | 3 (33) | 10 (43) | 10 (45) | – |
 Digitalis glycosides | 3 (33) | 11 (48) | 4 (18) | – |
 Anticoagulant | 1 (11) | 5 (22) | 2 (9) | – |
 (ARB) angiotensin II antagonists | 0 | 5 (22) | 1 (4.5) | – |
 Antiplatelet medications | 0 | 5 (22) | 3 (14) | – |