Variable | Univariate analysis | |
---|---|---|
HR (95% CI) | P | |
Gender | ||
 Male | Reference |  |
 Female | 1.088 (0.678–1.746) | 0.726 |
Age (years) | ||
 ≤ 42 | Reference |  |
 > 42 | 0.316 (0.171–0.587) | < 0.001 |
Family history | Â | Â |
 Yes | Reference |  |
 No | 0.877 (0.512–1.501) | 0.631 |
Smoking behaviour | ||
 Yes | Reference |  |
 No | 0.965 (0.595–1.564) | 0.884 |
BMI | ||
 ≥ 25 | Reference |  |
 18.5 ≤ BMI < 25 | 1.419 (0.757–2.660) | 0.275 |
 < 18.5 | 1.489 (0.480–4.618) | 0.491 |
TNM stage | ||
 I | Reference |  |
 II | 1.058 (0.318–3.517) | 0.927 |
 III | 3.256 (1.477–7.181) | 0.003 |
 IV | 6.575 (2.939–14.711) | < 0.001 |
Size (cm)d | ||
 ≤ 6.3 | Reference |  |
 > 6.3 | 2.769 (1.503–5.101) | 0.001 |
Treatment | ||
 Surgery | Reference |  |
 Radiotherapy/chemotherapy | 3.737 (1.891–7.387) | < 0.001 |
 Surgery and radiotherapy/chemotherapy | 1.049 (0.517–2.126) | 0.895 |
 Other | 6.845 (2.630–17.818) | < 0.001 |
ALT (U/L) | ||
 ≤ 12.5 | Reference |  |
 > 12.5 | 0.630 (0.311–1.278) | 0.200 |
AST (U/L) | ||
 ≤ 22.0 | Reference |  |
 > 22.0 | 1.366 (0.849–2.197) | 0.198 |
SLR | ||
 ≤ 1.24 | Reference |  |
 > 1.24 | 1.673 (1.015–2.759) | 0.044 |
APOAI (g/L) | ||
 ≤ 1.17 | Reference |  |
 > 1.17 | 0.393 (0.244–0.633) | < 0.001 |
APOB (g/L) | ||
 ≤ 0.99 | Reference |  |
 > 0.99 | 0.533 (0.308–0.922) | 0.024 |
ALP (U/L) | ||
 ≤ 82.9 | Reference |  |
 > 82.9 | 1.800 (1.106–2.929) | 0.018 |
ALB (g/L) | ||
 ≤ 40.1 | Reference |  |
 > 40.1 | 0.693 (0.385–1.246) | 0.220 |
GGT (U/L) | ||
 ≤ 44.2 | Reference |  |
 > 44.2 | 2.371 (1.348–4.169) | 0.003 |
LDH (U/L) | ||
 ≤ 245.6 | Reference |  |
 > 245.6 | 3.423 (1.847–6.345) | < 0.001 |
TBIL (μmol/L) | ||
 ≤ 13.6 | Reference |  |
 > 13.6 | 0.541 (0.276–1.059) | 0.073 |
DBIL (μmol/L) | ||
 ≤ 3.3 | Reference |  |
 > 3.3 | 1.583 (0.974–2.572) | 0.064 |