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Table 1 Patient demographics and clinical characteristics

From: Establishment and validation of a predictive nomogram model for non-small cell lung cancer patients with chronic hepatitis B viral infection

 

Primary cohort

Validation cohort

n = (141)

n = (89)

Characteristic

No. (%)

No. (%)

 Gender

  Male

72 (51.1%)

50 (56.2%)

  Female

69 (48.9%)

39 (43.8%)

 Age (years)

  ≤ 42

19 (13.5%)

11 (12.4%)

  > 42

122 (86.5%)

78 (87.6%)

 Family history

  Yes

36 (25.5%)

18 (20.2%)

  No

105 (74.5%)

71 (79.8%)

 Smoking behaviour

  Yes

84 (59.6%)

50 (56.2%)

  No

57 (40.4%)

39 (43.8%)

 BMI

  ≥ 25

30 (21.3%)

14 (15.7%)

  18.5 ≤ BMI < 25

103 (73.0%)

65 (73.0%)

  < 18.5

8 (5.7%)

10 (11.3%)

 TNM stagea

  I

31 (22.0%)

23 (25.8%)

  II

17 (12.1%)

6 (6.7%)

  III

53 (37.6%)

34 (38.2%)

  IV

40 (28.3%)

26 (29.3%)

 Size (cm)b

  ≤ 6.3

122 (86.5%)

70 (78.7%)

  > 6.3

19 (13.5%)

19 (21.3%)

 Treatment

  Surgery

37 (26.2%)

21 (23.6%)

  Radiotherapy/chemotherapy

47 (33.3%)

31 (34.8%)

  Surgery and radiotherapy/chemotherapy

49 (34.8%)

25 (28.1%)

  Other

8 (5.7%)

12 (13.5%)

 ALT (U/L)

  ≤ 12.5

15 (10.6%)

11 (12.4%)

  > 12.5

126 (89.4%)

78 (87.6%)

 AST (U/L)

  ≤ 22.0

73 (51.8%)

45 (50.1%)

  > 22.0

68 (48.2%)

44 (49.9%)

 SLR

  ≤ 1.24

102 (72.3%)

61 (68.5%)

  > 1.24

39 (27.7%)

28 (31.5%)

 APOAI (g/L)

  ≤ 1.17

56 (39.7%)

39 (43.8%)

  > 1.17

85 (60.3%)

50 (56.2%)

 APOB (g/L)

  ≤ 0.99

92 (65.2%)

50 (56.2%)

  > 0.99

49 (34.8%)

39 (43.8%)

 ALP (U/L)

  ≤ 82.9

96 (68.1%)

51 (57.3%)

  > 82.9

45 (31.9%)

38 (42.7%)

 ALB (g/L)

  ≤ 40.1

108 (76.6%)

62 (69.7%)

  > 40.1

33 (23.4%)

27 (30.3%)

 GGT (U/L)

  ≤ 44.2

117 (83.0%)

72 (80.9%)

  > 44.2

24 (17.0%)

17 (19.1%)

 LDH (U/L)

  ≤ 245.6

125 (88.7%)

77 (86.5%)

  > 245.6

16 (11.2%)

12 (13.5%)

 TBIL (μmol/L)

  ≤ 13.6

113 (80.1%)

61 (68.5%)

  > 13.6

28 (19.9%)

28 (31.5%)

 DBIL (μmol/L)

  ≤ 3.3

67 (47.5%)

38 (42.7%)

  > 3.3

74 (52.5%)

51 (57.2%)

  1. BMI body mass index, TNM pathological tumour node metastasis stage, ALT alanine transaminase, AST aspartate aminotransferase, SLR AST-to-ALT ratio, APOAI apolipoprotein AI, APOB apolipoprotein B, ALP alkaline phosphatase, ALB albumin, GGT glutamyl transpeptidase, LDH lactic dehydrogenase, TBIL total bilirubin, DBIL direct bilirubin
  2. aTNM stage was classified according to the AJCC 7th TNM staging system
  3. bThe tumor maximum diameter