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Table 1 Transcripts showing the highest up-regulation measured using the U133 human genome array (Affymetrix) in severe fibrosis relative to normal histology

From: CCL20 is up-regulated in non-alcoholic fatty liver disease fibrosis and is produced by hepatic stellate cells in response to fatty acid loading

Gene

Gene name

SLR

CCL20

C-C motif chemokine ligand 20

5.9

STMN2

Stathmin 2

5.3

IGHM

Ig rearranged mu-chain gene V-N-D-N-J-region

4.1

RTN1

Reticulon 1

4.0

IGL

Immunoglobulin lambda gene locus DNA, clone:84E4

3.9

AKR1B10

Aldo–keto reductase family 1, member B10

3.8

LCK

Lymphocyte-specific protein tyrosine kinase

3.4

DEFA1

Defensin, alpha 1

3.4

COL15A1

Collagen, type XV, alpha 1

3.2

  1. SLR signal log ratio