Fig. 3
From: Role of p53/miR-155-5p/sirt1 loop in renal tubular injury of diabetic kidney disease
The Sirt1 3′UTR is regulated by miR-155-5p. a MiR-155-5p and its putative binding sequence in the 3′UTR of Sirt1. Luciferase assay of HK-2 cells co-transfected with miR-155 inhibitors (b) or mimics (c) and the luciferase reporter. The experiments were performed in triplicate. The data are expressed as the mean ± SEM. *P < 0.05. miR-155-i miR-155 inhibitor, miR-inhibit-NC miRNA inhibit negative control, miR-155-m miR-155 mimics, miR-mimic-NC miRNA mimic negative control