Table 1 Clinical characteristics and result of clinical and molecular tests administered to RPL and controls women

Age (years) ± SD

34.7 ± 6.7

37.3 ± 4.3

NS

BMI (Kg/m²)

21.9 ± 2.8

24.4 ± 3.4

NS

IVF (n)

0.0 (0.0%)

3.0 (4.3%)

NS

Intestinal permeability (%) ± SD

2.2 ± 0.3

6.4 ± 0.7

< 0.0001

Serum LPS levels (EU/ml) ± SD

0.3 ± 0.1

0.9 ± 0.1

< 0.05

Anxiety state (STAI-Y1) (%)

35.0

87.0

< 0.05

Anxiety trait (STAI-Y2) (%)

31.0

60.0

< 0.05

Depression state (Zung scale) (%)

24.0

48.0

< 0.05

Abnormal endometrial Nalp-3 expression (%)

0.3

85.7 [n = 35]

< 0.0001