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Table 1 Criteria for inclusion and exclusion

From: The release of cardioprotective humoral factors after remote ischemic preconditioning in humans is age- and sex-dependent

Criteria for inclusion

Written informed consent

Age: 18–30 or 60–80 years, respectively

Adequate age-based response to physical stress

Normal performance of upper limbs

Criteria for exclusion

Missing consent

Long-term medication

Acute medication (within the past 14 days)

Peripheral arterial disease

Diabetes mellitus

Hypertension, NYHA > II

Pre-existing nerve damage of the upper limb

Status after thrombo-embolic events

Smoking (within the past 5 years, > 10 pack years)

Pregnancy

Chronic pain disorders and psychiatric or neurologic disorders leading to missing legal competence