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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Contribution of TLR4 signaling in intermittent hypoxia-mediated atherosclerosis progression

Fig. 3

Instability of atherosclerotic plaque. a OilRed O staining image and quantification of lipid deposition. b Quantification of plaque macrophage content by immunohistochemical MOMA-2 staining. c Quantification of plaque smooth muscle cell content by immunohistochemical α-SMA staining. d Picrosirius Red staining image and quantification of plaque collagen I content. e Plaque vulnerability index [(Oil Red O + area plus MOMA-2 + area)/(α-SMA + area plus collagen I+ area)] in atherosclerotic plaque. Data represent mean ± SEM of four separate samples.*p < 0.05 versus Sham group and #p < 0.05 versus IH + LV-EGFP group

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