Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection

Table 4 Percentage of participants experiencing criteria-defined, non-mandatory symptoms for three levels of ME/CFS severity (increasing order of occurrence from healthy/mild to severe cohorts)

Criterion	Healthy/mild % (n = 24)	Moderate % (n = 21)	Severe % (n = 14)	p value (χ² test)
Headaches monthly	0	14	21	0.0801
Migraine	0	14	7	0.1636
Headaches daily	8	43	28	0.0282*
Sensitive to smell	8	52	57	0.0014*
Sensitive to touch	13	23	36	0.2425
Headaches weekly	13	29	36	0.217

All mild to severe cases reported > 6-months fatigue and post exertional malaise
* Statistical significance at p < 0.05

ISSN: 1479-5876