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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: The physiological role of Motin family and its dysregulation in tumorigenesis

Fig. 3

Expression pattern of Motin family members in various cancer types which have been reported previously. a According to GENT database, there is discrepancy of expression regarding to AMOT in different tumors. When compared to correspondingly normal control, its expression level is significantly lower in breast cancer (P < 0.001), kidney cancer (P = 0.002), as well as head and neck tumor (P = 0.008); however, AMOT is overexpressed in colon cancer (P = 0.003) and lung cancer (P = 0.018). The difference of AMOT expression between prostate cancer and the corresponding normal is insignificant (P = 0.230). b AMOTL1 exhibits downregulation in both breast cancer (P < 0.001) and cervical cancer (P < 0.001). c Expression of AMOTL2 is only down-regulated in breast cancer (P < 0.001), rather than brain cancer (P = 0.353)

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