Fig. 4
From: Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment
High ratio TRIM28 stromal tissue shows low levels of MDM2 and high levels of COX-2. Box-plot diagrams of a MDM2 and b COX-2 represent RPPA intensity levels in the epithelium and stroma of TRIM28 high and low ratio cases. MDM2 is downregulated in stroma of TRIM28 high Ratio cases (p = 0.010, a). COX2 is elevated in stroma in TRIM28 high ratio cases were found (p = 0.002, b). The median (line within the box), mean (center of the diamond), 25th and 75th percentiles and maximum and minimum values are all displayed on each box-plot