Genotype | n | Mean ± SE (day) | Median (range) (day) | HR (95% CI) | P | HR (95% CI)a | P a |
---|---|---|---|---|---|---|---|
NME1 rs3760468 | |||||||
 AA | 135 | 1326 ± 209 | 1534 (947–2121) | 1.00 (reference) |  | 1.00 (reference) |  |
 AT | 160 | 1232 ± 218 | 768 (388–1148) | 1.238 (0.890–1.724) | 0.205 | 1.455 (1.015–2.087) | 0.041 |
 TT | 47 | 801 ± 231 | 513 (398–638) | 1.652 (1.067–2.557) | 0.024 | 1.702 (1.072–2.704) | 0.024 |
 AT+TT | 207 | 1159 ± 185 | 663 (442–884) | 1.328 (0.973–1.812) | 0.073 | 1.518 (1.082–2.129) | 0.016 |
NME2 rs3744660 | |||||||
 GG | 230 | 1283 ± 168 | 1159 (615–1703) | 1.00 (reference) |  | 1.00 (reference) |  |
 AG | 98 | 1175 ± 252 | 817 (410–1224) | 1.283 (0.924–1.780) | 0.137 | 1.181 (0.831–1.679) | 0.353 |
 AA | 15 | 442 ± 149 | 359 (167–551) | 2.214 (1.154–4.247) | 0.017 | 2.284 (1.145–4.559) | 0.019 |
 GG+AG | 328 | 1261 ± 143 | 988 (682–1294) | 1.00 (reference) |  | 1.00 (reference) |  |
 AA | 15 | 442 ± 149 | 359 (167–511) | 2.054 (1.080–3.905) | 0.025 | 2.172 (1.098–4.294) | 0.026 |
RRM1 rs183484 | |||||||
 GG | 109 | 940 ± 167 | 672 (454–890) | 1.00 (reference) |  | 1.00 (reference) |  |
 GT | 194 | 1506 ± 202 | 1749 (799–2699) | 0.692 (0.496–0.964) | 0.030 | 0.599 (0.413–0.868) | 0.007 |
 TT | 46 | 993 ± 305 | 414 (162–666) | 1.112 (0.717–1.726) | 0.635 | 1.063 (0.665–1.698) | 0.799 |
RRM2 rs1130609 | |||||||
 TT | 148 | 1243 \± 201 | 1025 (426–1624) | 1.00 (reference) |  | 1.00 (reference) |  |
 GT | 161 | 1380 ± 209 | 843 (520–1166) | 0.988 (0.719–1.357) | 0.941 | 1.025 (0.746–1.408) | 0.881 |
 GG | 36 | 753 ± 248 | 473 (137–809) | 1.506 (0.917–2.475) | 0.106 | 1.489 (0.906–2.448) | 0.116 |
 TT+GT | 309 | 1297 ± 153 | 935 (645–1225) | 1.00 (reference) |  | 1.00 (reference) |  |
 GG | 36 | 753 ± 248 | 473 (137–809) | 1.516 (0.948–2.422) | 0.080 | 1.471 (0.920–2.352) | 0.107 |