Genotype | Total (n) | CR, n (%) | Non-CR, n (%) | P | OR (95% CI) | P a | OR (95% CI)a |
---|---|---|---|---|---|---|---|
CMPK1 rs7543016 | |||||||
 CC | 93 | 57 (61.3%) | 36 (38.7%) |  | 1.00 (reference) |  | 1.00 (reference) |
 GC | 167 | 106 (63.5%) | 61 (36.5%) | 0.727 | 0.911 (0.540–1.537) | 0.921 | 0.970 (0.531–1.772) |
 GG | 30 | 23 (76.7%) | 7 (23.3%) | 0.125 | 0.482 (0.188–1.238) | 0.076 | 0.365 (0.120–1.111) |
NME1 rs3760468 | |||||||
 AA | 115 | 77 (67.0%) | 38 (33.0%) |  | 1.00 (reference) |  | 1.00 (reference) |
 AT | 154 | 96 (62.3%) | 58 (37.7%) | 0.434 | 1.224 (0.737–2.033) | 0.256 | 1.420 (0.775–2.597) |
 TT | 44 | 26 (59.1%) | 18 (40.9%) | 0.353 | 1.403 (0.686–2.869) | 0.465 | 1.359 (0.597–3.096) |
NME1 rs2302254 | |||||||
 CC | 186 | 123 (66.1%) | 63 (33.9%) |  | 1.00 (reference) |  | 1.00 (reference) |
 CT | 114 | 65 (57.0%) | 49 (43.0%) | 0.114 | 1.473 (0.912–2.375) | 0.288 | 1.355 (0.775–2.370) |
 TT | 19 | 13 (68.4%) | 6 (31.6%) | 0.840 | 0.901 (0.327–2.481) | 0.534 | 0.688 (0.212–2.232) |
NME2 rs3744660 | |||||||
 GG | 213 | 146 (68.5%) | 67 (31.5%) |  | 1.00 (reference) |  | 1.00 (reference) |
 AG | 89 | 48 (53.9%) | 41 (46.1%) | 0.016 | 1.861 (1.121–3.091) | 0.024 | 1.953 (1.092–3.484) |
 AA | 14 | 8 (57.1%) | 6 (42.9%) | 0.376 | 1.634 (0.545–4.897) | 0.770 | 1.299 (0.361–4.673) |
 AA+AG | 103 | 56 (54.4%) | 47 (45.6%) | 0.014 | 1.829 (1.127–2.967) | 0.030 | 1.852 (1.062–3.236) |
SAMHD1 rs6102991 | |||||||
 AA | 88 | 49 (55.7%) | 39 (44.3%) |  | 1.00 (reference) |  | 1.00 (reference) |
 GA | 161 | 107 (66.5%) | 54 (33.5%) | 0.093 | 0.634 (0.372–1.080) | 0.183 | 0.669 (0.370–1.209) |
 GG | 62 | 43 (69.4%) | 19 (30.6%) | 0.090 | 0.555 (0.280–1.101) | 0.063 | 0.483 (0.224–1.038) |
 AG+GG | 223 | 150 (67.3%) | 73 (32.7%) | 0.055 | 0.611 (0.369–1.013) | 0.086 | 0.611 (0.349–1.071) |
SAMHD1 rs28372906 | |||||||
 TT | 284 | 180 (63.4%) | 104 (36.6%) |  | 1.00 (reference) |  | 1.00 (reference) |
 CT | 32 | 21 (65.6%) | 11 (34.4%) | 0.802 | 0.907 (0.420–1.955) | 0.878 | 0.935 (0.394–2.217) |
 CC | 4 | 3 (75.0%) | 1 (25.0%) | 0.632 | 0.577 (0.059–5.618) | 0.953 | 0.933 (0.091–9.524) |
SAMHD1 rs6029941 | |||||||
 GG | 88 | 50 (56.8%) | 38 (43.2%) |  | 1.00 (reference) |  | 1.00 (reference) |
 GA | 161 | 107 (66.5%) | 54 (33.5%) | 0.132 | 0.664 (0.389–1.132) | 0.339 | 0.739 (0.398–1.374) |
 AA | 65 | 42 (64.6%) | 23 (35.4%) | 0.330 | 0.721 (0.372–1.395) | 0.370 | 0.706 (0.330–1.512) |
E2F1 rs3213180 | |||||||
 GG | 149 | 95 (63.8%) | 54 (36.2%) |  | 1.00 (reference) |  | 1.00 (reference) |
 GC | 141 | 90 (63.8%) | 51 (36.2%) | 0.990 | 0.997 (0.617–1.610) | 0.915 | 0.970 (0.552–1.704) |
 CC | 29 | 16 (55.2%) | 13 (44.8%) | 0.383 | 1.429 (0.639–3.195) | 0.429 | 1.449 (0.578–3.636) |
E2F1 rs3213150 | |||||||
 CC | 111 | 67 (60.4%) | 44 (39.6%) |  | 1.00 (reference) |  | 1.00 (reference) |
 CT | 159 | 110 (69.2%) | 49 (30.8%) | 0.133 | 0.678 (0.408–1.127) | 0.105 | 0.616 (0.343–1.106) |
 TT | 46 | 23 (50.0%) | 23 (50.0%) | 0.232 | 1.523 (0.762–3.042) | 0.128 | 1.835 (0.839–4.016) |
 CC+CT | 270 | 177 (65.6%) | 93 (34.4%) |  | 1.00 (reference) |  | 1.00 (reference) |
 TT | 46 | 23 (50.0%) | 23 (50.0%) | 0.043 | 1.903 (1.014–3.574) | 0.033 | 2.208 (1.065–4.567) |
RRM1 rs183484 | |||||||
 GG | 100 | 62 (62.0%) | 38 (38.0%) |  | 1.00 (reference) |  | 1.00 (reference) |
 GT | 177 | 118 (66.7%) | 59 (33.3%) | 0.434 | 0.816 (0.490–1.359) | 0.112 | 0.617 (0.340–1.119) |
 TT | 42 | 22 (52.4%) | 20 (47.6%) | 0.287 | 1.483 (0.716–3.071) | 0.263 | 1.616 (0.697–3.731) |
RRM1 rs2412344 | |||||||
 TT | 89 | 56 (62.9%) | 33 (37.1%) |  | 1.00 (reference) |  | 1.00 (reference) |
 CT | 183 | 119 (65.0%) | 64 (35.0%) | 0.734 | 0.913 (0.539–1.545) | 0.510 | 0.817 (0.449–1.488) |
 CC | 48 | 28 (58.3%) | 20 (41.7%) | 0.599 | 1.212 (0.592–2.483) | 0.967 | 1.018 (0.429–2.415) |
RRM2 rs1130609 | |||||||
 TT | 131 | 84 (64.1%) | 47 (35.9%) |  | 1.00 (reference) |  | 1.00 (reference) |
 GT | 149 | 100 (67.1%) | 49 (32.9%) | 0.599 | 0.876 (0.534–1.436) | 0.920 | 0.972 (0.557–1.697) |
 GG | 34 | 15 (44.1%) | 19 (55.9%) | 0.034 | 2.264 (1.053–4.867) | 0.069 | 2.347 (0.935–5.882) |
 TT+GT | 280 | 184 (65.7%) | 96 (34.3%) |  | 1.00 (reference) |  | 1.00 (reference) |
 GG | 34 | 15 (44.1%) | 19 (55.9%) | 0.014 | 2.428 (1.181–4.990) | 0.044 | 2.398 (1.025–5.618) |