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Table 1 The characteristics of enrolled individuals

From: Association between serum S100A9 levels and liver necroinflammation in chronic hepatitis B

Parameters CHB (n = 183) HCs (n = 49) p value
HBeAg(−) HBeAg(+) CHB vs HCs
Inactive carrier (n = 13) Immune reactivation (n = 79) Immune-tolerant (n = 23) Immune-active phase (n = 68)
Gender (male, %) 10 (76.9%) 57 (72.1%) 13 (56.5%) 38 (55.8%) 36 (73.4%) > 0.05
Age (years) 37 (9) 47 (19) 39 (10) 41 (12) 37 (14) > 0.05
ALT (U/L) 23 (19.5) 54 (56) 34 (15) 145 (314) 19 (16.8) < 0.01
AST (U/L) 24 (11.5) 52 (46) 21 (9) 113 (208) 21 (15.4) < 0.01
HBV DNA (log10 IU/ml) 2.58 (1.95) 4.3 (2.45) 6.32 (1.79) 5.48 (2.17) N/A  
HBsAg (log10 IU/ml) 3.02 (0.57) 3.34 (0.97) 4.02 (0.95) 4.63 (1.7) N/A  
Grading of necroinflammation (n) G0/G1/G2/G3/G4 9/4/0/0/0 10/37/16/12/4 4/19/0/0/0 1/1/22/22/22   
Stage of fibrosis (n) S0/S1/S2/S3/S4 (S4: cirrhosis) 8/5/0/0/0 5/16/25/23/10 7/16/0/0/0/ 2/7/24/22/13   
  1. For age, ALT, AST, HBV DNA titres and HBsAg, data are presented as median (interquartile range)
  2. N/A not available
  3. p values < 0.05 are considered as significant