Table 1 The characteristics of enrolled individuals
From: Association between serum S100A9 levels and liver necroinflammation in chronic hepatitis B
Parameters | CHB (n = 183) | HCs (n = 49) | p value | |||
|---|---|---|---|---|---|---|
HBeAg(−) | HBeAg(+) | CHB vs HCs | ||||
Inactive carrier (n = 13) | Immune reactivation (n = 79) | Immune-tolerant (n = 23) | Immune-active phase (n = 68) | |||
Gender (male, %) | 10 (76.9%) | 57 (72.1%) | 13 (56.5%) | 38 (55.8%) | 36 (73.4%) | > 0.05 |
Age (years) | 37 (9) | 47 (19) | 39 (10) | 41 (12) | 37 (14) | > 0.05 |
ALT (U/L) | 23 (19.5) | 54 (56) | 34 (15) | 145 (314) | 19 (16.8) | < 0.01 |
AST (U/L) | 24 (11.5) | 52 (46) | 21 (9) | 113 (208) | 21 (15.4) | < 0.01 |
HBV DNA (log10 IU/ml) | 2.58 (1.95) | 4.3 (2.45) | 6.32 (1.79) | 5.48 (2.17) | N/A | Â |
HBsAg (log10 IU/ml) | 3.02 (0.57) | 3.34 (0.97) | 4.02 (0.95) | 4.63 (1.7) | N/A | Â |
Grading of necroinflammation (n) G0/G1/G2/G3/G4 | 9/4/0/0/0 | 10/37/16/12/4 | 4/19/0/0/0 | 1/1/22/22/22 | Â | Â |
Stage of fibrosis (n) S0/S1/S2/S3/S4 (S4: cirrhosis) | 8/5/0/0/0 | 5/16/25/23/10 | 7/16/0/0/0/ | 2/7/24/22/13 | Â | Â |