Fig. 4

Dexmedetomidine inhibits IR serum-Induced apoptosis of PMVECs. Cells were treated with 0.1–10 μM DEX 30 min before receiving 15% IR serum stimulation. a Hoechst 33258 staining in PMVECs. b Cell apoptosis measured by flow cytometry. c The percentage of apoptotic cells. The 15% sham serum stimulated group was used as control. Bar represents a length of 50 μm. Data are shown as mean ± SD. **p < 0.01 versus sham group, ^##p < 0.01 versus IR group