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Table 1 SLC44A2 allele distribution and HNA-3 antigens predicted by genotype

From: HNA-3a and HNA-3b antigens among 9 ethnic populations and the Han population in Southwest China

Blood donors Genotypes SLC44A2 allele frequency Hardy–Weinberg Chance of being exposed to an alloimmunization risk against HNA-3a
Population group Ethnicity Location Province n HNA-3a/a HNA-3a/b HNA-3b/b HNA-3a HNA-3b χ2 P
Minority Yi Honghe Yunnan 120 61 (51%) 53 (44%) 6 (5%)a 0.73 0.27b,c 1.67 0.2 0.068
   Chuxiong Yunnan 153 82 (54%) 58 (38%) 13 (8%)a 0.73 0.27b,c 0.36 0.55 0.068
   Luquan Yunnan 122 55 (45%) 56 (46%) 11 (9%)a 0.68 0.32d 0.37 0.54 0.092
   Shilin Yunnan 83 39 (47%) 33 (40%) 11 (13%) 0.67 0.33d 0.88 0.35 0.097
   Xichang Sichuan 144 57 (40%) 59 (41%) 28 (19%) 0.60 0.40 3.06 0.08 0.134
  Zhuang Wenshan Yunnan 196 115 (59%) 69 (35%) 12 (6%)a 0.76 0.24b,c 0.15 0.70 0.054
  Derung Nujiang Yunnan 184 107 (58%) 62 (34%) 15 (8%)a 0.75 0.25b,c 1.89 0.17 0.059
  Hani Honghe Yunnan 190 119 (63%) 59 (31%) 12 (6%)a 0.78 0.22 1.56 0.21 0.046
  Lisu Lijiang Yunnan 254 146 (57%) 87 (34%) 21 (8%)a 0.75 0.25b,c 2.34 0.13 0.059
  Bai Dali Yunnan 190 95 (50%) 79 (42%) 16 (8%)a 0.71 0.29 0.01 0.94 0.077
  Miao Wenshan Yunnan 209 101 (48%) 90 (43%) 18 (9%)a 0.70 0.30d 0.11 0.74 0.082
  Dai Xishuangbanna Yunnan 126 62 (49%) 51 (40%) 13 (10%) 0.69 0.31 0.27 0.60 0.087
  Naxi Lijiang Yunnan 187 85 (45%) 86 (46%) 16 (9%)a 0.68 0.32 0.78 0.38 0.092
Majority Han Yunnan Yunnan 192 67 (35%) 102 (53%) 23 (12%) 0.61 0.39d 2.83 0.09 0.129
  Han Sichuan Sichuan 232 94 (41%) 113 (49%) 25 (11%) 0.65 0.35 1.09 0.30 0.107
  1. Differences were significant when P < 0.05
  2. aThe genotype frequency significantly differs compared to Sichuan Yi (Chi square test)
  3. bThe allele frequency significantly differs compared to Sichuan Yi (Chi square test)
  4. cThe allele frequency significantly differs compared to Sichuan Han (Chi square test)
  5. dThe allele frequency significantly differs compared to Yunnan Zhuang (Chi square test)