Table 1 Clinical characteristics of patients with aberrant expressed miR-362-5p
From: MiR-362-5p as a novel prognostic predictor of cytogenetically normal acute myeloid leukemia
Variables | Low expression | High expression | P value |
|---|---|---|---|
Number | 112 | 112 | |
Sex, n (%) | 60 (53.6) | 71 (63.4) | 0.175 |
Age, years# | 45.50 [33.00, 59.00] | 50.50 [41.25, 62.00] | 0.048 |
WBC, 109/l# | 18.60 [4.79, 64.65] | 28.30 [5.80, 93.55] | 0.301 |
Hemoglobin, /l# | 79.50 [66.00, 95.00] | 88.50 [67.00, 105.25] | 0.061 |
PLT, 109/l# | 38.50 [22.75, 77.25] | 46.50 [25.00, 109.50] | 0.141 |
Blast, %# | 69.00 [54.00, 79.62] | 71.50 [48.38, 82.62] | 0.920 |
FAB subtype, n (%) | 0.904 | ||
M0 | 9 (8.0) | 11 (9.8) | |
M1 | 12 (10.7) | 11 (9.8) | |
M2 | 47 (42.0) | 50 (44.6) | |
M4 | 14 (12.5) | 9 (8.0) | |
M5 | 28 (25.0) | 28 (25.0) | |
M6 | 2 (1.8) | 3 (2.7) | |
Genes mutation, n (%) | |||
FLT3-ITD | 19 (17.0) | 24 (21.4) | 0.498 |
CEBPADM& | 14 (12.5) | 17 (15.2) | 0.699 |
NPM1 | 21 (18.8) | 33 (29.5) | 0.085 |
DNMT3A | 10 (8.9) | 12 (10.7) | 0.823 |
IDH1 | 7 (6.2) | 12 (10.7) | 0.338 |
IDH2 | 11 (9.8) | 19 (17.0) | 0.169 |
CR rates | 76 (67.9) | 63 (56.2) | 0.098 |