Fig. 2

DAPT reduces IMQ-induced splenomegaly mice were euthanized after 7 consecutive days of experimental process, and the spleen mass (a) and spleen index (b) were observed. Compared to control mice, the spleen mass and spleen index of IMQ-treated mice were significant increased (^#P < 0.01), while combined treatment of DAPT and IMQ led to the reduction of spleen mass and spleen index to a great degree (^#P < 0.01)