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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Oral Escherichia coli expressing IL-35 meliorates experimental colitis in mice

Fig. 5

Effects of E. coli/IL-35 on the regulation of IL-10 and IL-6 expressions in colon. The mRNA levels of IL-10 and IL-6 were analyzed by real-time PCR. a E. coli/IL-35 treatment increased IL-10 mRNA expression in colon tissues in DSS-induced colitis mice. b E. coli/IL-35 intake reduced IL-6 mRNA expression in colon tissues in DSS-induced colitis mice. n = 10 mice per group. Compared with the DSS group, *p < 0.05; compared with the DSS + E. coli/0 group, *p < 0.05. c DSS intake remarkably reduce IL-12p40 expression and E. coli/IL-35 treatment did not change the tendency (*p < 0.01)

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