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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Oral Escherichia coli expressing IL-35 meliorates experimental colitis in mice

Fig. 4

E. coli/IL-35 treatment affected the proportions of Treg and Th17 cells in spleens and MLN. The representative images of flow cytometry for splenocytes and MLN were shown while positive cells were counted from the quadrant Q4. E. coli/IL-35 bacteria increased CD4+CD25+Foxp3+ cells (Treg cells) but reduced IL-17A cells (Th17 cells) in the spleens (a) and MLN (b) from UC mice, which had lower proportion of Treg cells and higher proportion of Th17 cells as compared to normal controls. Compared with the DSS group, *p < 0.05; compared with the DSS + E. coli/0 group, *p < 0.05

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