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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: OX40L induces helper T cell differentiation during cell immunity of asthma through PI3K/AKT and P38 MAPK signaling pathway

Fig. 5

The effect of OX40L-Ig fusion protein and anti-mouse-OX40L mAb on Th cells differentiation in asthma models. Control: challenged mice with Saline; OVA: sensitized and challenged mice with OVA; OVA + IgG: OVA-primed mice treated with IgG; OVA + OX40L: OVA-reduced mice treated with OX40L-Ig fusion protein; OVA + anti-OX40L: OVA-reduced mice treated with anti-mouse-OX40L mAb. a–d The expression of IFN-γ, IL-4 and IL-17 and TGF-β. e–h Cells count of Th1, Th2, Th17 and Treg. *p < 0.05 versus control, #p <  0.05 versus OVA

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